1 Zirmire, R. K. et al. Bacopa monnieri phytochemicals regulate fibroblast cell migration via modulation of focal adhesions. iScience 27, 109489 (2024). https://doi.org:10.1016/j.isci.2024.109489
2 Hegde, A. et al. Extracellular Caspase-1 induces hair stem cell migration in wounded and inflamed skin conditions. J Cell Biol 223 (2024). https://doi.org:10.1083/jcb.202306028
3 Dutta, A., Saha, D. & Jamora, C. Approaches to Study Wound-Induced Hair Neogenesis (WIHN). Methods Mol Biol (2024). https://doi.org:10.1007/7651_2024_522
4 Asokan, M. S. et al. Immunogenicity of SARS-CoV-2 vaccines BBV152 (COVAXIN(R)) and ChAdOx1 nCoV-19 (COVISHIELD) in seronegative and seropositive individuals in India: a multicentre, nonrandomised observational study. Lancet Reg Health Southeast Asia 22, 100361 (2024). https://doi.org:10.1016/j.lansea.2024.100361
5 Rana, I. et al. Mindin (SPON2) Is Essential for Cutaneous Fibrogenesis in a Mouse Model of Systemic Sclerosis. J Invest Dermatol 143, 699-710 e610 (2023). https://doi.org:10.1016/j.jid.2022.10.011
6 Patlolla, N., Ponnachan, P., Jamora, C. & Abbey, D. Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor. Stem Cell Res 69, 103112 (2023). https://doi.org:10.1016/j.scr.2023.103112
7 Bhatt, T. et al. Niacinamide enhances cathelicidin mediated SARS-CoV-2 membrane disruption. Front Immunol14, 1255478 (2023). https://doi.org:10.3389/fimmu.2023.1255478
8 Zaarour, R. F. et al. The neuropeptide Substance P facilitates the transition from an inflammatory to proliferation phase-associated responses in dermal fibroblasts. Exp Dermatol 31, 1188-1201 (2022). https://doi.org:10.1111/exd.14573
9 Sobecki, M. et al. Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell Stem Cell 29, 1459-1474 e1459 (2022). https://doi.org:10.1016/j.stem.2022.08.012
10 Hajam, E. Y. et al. The expanding impact of T-regs in the skin. Front Immunol 13, 983700 (2022). https://doi.org:10.3389/fimmu.2022.983700
11 Bhatt, T. et al. Initiation of wound healing is regulated by the convergence of mechanical and epigenetic cues. PLoS Biol 20, e3001777 (2022). https://doi.org:10.1371/journal.pbio.3001777
12 Badarinath, K. et al. Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin. Cell Rep 40, 111390 (2022). https://doi.org:10.1016/j.celrep.2022.111390
13 Zaarour, R. F. et al. Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival. Cancers (Basel) 13(2021). https://doi.org:10.3390/cancers13030533
14 Saha, D., Thannimangalath, S., Budamakuntla, L., Loganathan, E. & Jamora, C. Hair Follicle Grafting Therapy Promotes Re-Emergence of Critical Skin Components in Chronic Nonhealing Wounds. JID Innov 1, 100041 (2021). https://doi.org:10.1016/j.xjidi.2021.100041
15 Rana, I., Badarinath, K., Zirmire, R. K. & Jamora, C. Isolation and Quantification of Mouse gammadeltaT-cells in vitro and in vivo. Bio Protoc 11, e4148 (2021). https://doi.org:10.21769/BioProtoc.4148
16 Gund, R., Zirmire, R., J, H., Kansagara, G. & Jamora, C. Histological and Immunohistochemical Examination of Stem Cell Proliferation and Reepithelialization in the Wounded Skin. Bio Protoc 11, e3894 (2021). https://doi.org:10.21769/BioProtoc.3894
17 Biswas, R. et al. Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells. Dev Cell 56, 761-780 e767 (2021). https://doi.org:10.1016/j.devcel.2021.02.020
18 Bhatt, T. et al. Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8. Cell Rep 29, 2546-2555 e2544 (2019). https://doi.org:10.1016/j.celrep.2019.10.090
19 Badarinath, K. et al. Interactions Between Epidermal Keratinocytes, Dendritic Epidermal T-Cells, and Hair Follicle Stem Cells. Methods Mol Biol 1879, 285-297 (2019). https://doi.org:10.1007/7651_2018_155
20 Pincha, N., Saha, D., Bhatt, T., Zirmire, R. K. & Jamora, C. Activation of Fibroblast Contractility via Cell-Cell Interactions and Soluble Signals. Bio Protoc 8, e3021 (2018). https://doi.org:10.21769/BioProtoc.3021
21 Pincha, N. et al. PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest 128, 1807-1819 (2018). https://doi.org:10.1172/JCI99088
22 Lee, P. et al. Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of gammadeltaT-cells. Elife 6 (2017). https://doi.org:10.7554/eLife.28875
23 Nakasaki, M. et al. The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis.Nat Commun 6, 8574 (2015). https://doi.org:10.1038/ncomms9574
24 Lee, D. J. et al. Regulation and Function of the Caspase-1 in an Inflammatory Microenvironment. J Invest Dermatol 135, 2012-2020 (2015). https://doi.org:10.1038/jid.2015.119
25 Ando, T. et al. Mast Cells Are Required for Full Expression of Allergen/SEB-Induced Skin Inflammation. J Invest Dermatol 135, 925 (2015). https://doi.org:10.1038/jid.2014.359
26 Kim, J. et al. p53 Induces skin aging by depleting Blimp1+ sebaceous gland cells. Cell Death Dis 5, e1141 (2014). https://doi.org:10.1038/cddis.2014.87
27 Aung, A. et al. 3D traction stresses activate protease-dependent invasion of cancer cells. Biophys J 107, 2528-2537 (2014). https://doi.org:10.1016/j.bpj.2014.07.078
28 Ando, T. et al. Critical role for mast cell Stat5 activity in skin inflammation. Cell Rep 6, 366-376 (2014). https://doi.org:10.1016/j.celrep.2013.12.029
29 Cowburn, A. S. et al. HIF isoforms in the skin differentially regulate systemic arterial pressure. Proc Natl Acad Sci U S A 110, 17570-17575 (2013). https://doi.org:10.1073/pnas.1306942110
30 Bhatt, T., Rizvi, A., Batta, S. P., Kataria, S. & Jamora, C. Signaling and mechanical roles of E-cadherin. Cell Commun Adhes 20, 189-199 (2013). https://doi.org:10.3109/15419061.2013.854778
31 Ando, T. et al. Mast cells are required for full expression of allergen/SEB-induced skin inflammation. J Invest Dermatol 133, 2695-2705 (2013). https://doi.org:10.1038/jid.2013.250
32 Xu, J. et al. Fusarisetin A: Scalable Total Synthesis and Related Studies. Chem Sci 3, 3378-3386 (2012). https://doi.org:10.1039/C2SC21308G
33 Kanemaru, K. et al. Epidermal phospholipase Cdelta1 regulates granulocyte counts and systemic interleukin-17 levels in mice. Nat Commun 3, 963 (2012). https://doi.org:10.1038/ncomms1960
34 Swamy, M., Jamora, C., Havran, W. & Hayday, A. Epithelial decision makers: in search of the 'epimmunome'. Nat Immunol 11, 656-665 (2010). https://doi.org:10.1038/ni.1905
35 Li, C. et al. Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8. Proc Natl Acad Sci U S A 107, 22249-22254 (2010). https://doi.org:10.1073/pnas.1009751108
36 Du, F. et al. Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation. Cancer Res 70, 10080-10089 (2010). https://doi.org:10.1158/0008-5472.CAN-10-0324
37 Baldo, C., Jamora, C., Yamanouye, N., Zorn, T. M. & Moura-da-Silva, A. M. Mechanisms of vascular damage by hemorrhagic snake venom metalloproteinases: tissue distribution and in situ hydrolysis. PLoS Negl Trop Dis 4, e727 (2010). https://doi.org:10.1371/journal.pntd.0000727
38 Mielgo, A. et al. The death effector domains of caspase-8 induce terminal differentiation. PLoS One 4, e7879 (2009). https://doi.org:10.1371/journal.pone.0007879
39 Lee, P. et al. Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature 458, 519-523 (2009). https://doi.org:10.1038/nature07687
40 Boutin, A. T. et al. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell 133, 223-234 (2008). https://doi.org:10.1016/j.cell.2008.02.038
41 Jamora, C. et al. A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol 3, e11 (2005). https://doi.org:10.1371/journal.pbio.0030011
42 Perez-Moreno, M., Jamora, C. & Fuchs, E. Sticky business: orchestrating cellular signals at adherens junctions. Cell 112, 535-548 (2003). https://doi.org:10.1016/s0092-8674(03)00108-9
43 Jamora, C., DasGupta, R., Kocieniewski, P. & Fuchs, E. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422, 317-322 (2003). https://doi.org:10.1038/nature01458
44 Hoffman, L. M. et al. Targeted disruption of the murine zyxin gene. Mol Cell Biol 23, 70-79 (2003). https://doi.org:10.1128/MCB.23.1.70-79.2003
45 Jamora, C. & Fuchs, E. Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol 4, E101-108 (2002). https://doi.org:10.1038/ncb0402-e101
46 Jamora, C., Theodoraki, M. A., Malhotra, V. & Theodorakis, E. A. Investigation of the biological mode of action of clerocidin using whole cell assays. Bioorg Med Chem 9, 1365-1370 (2001). https://doi.org:10.1016/s0968-0896(01)00051-7
47 Fuchs, E., Merrill, B. J., Jamora, C. & DasGupta, R. At the roots of a never-ending cycle. Dev Cell 1, 13-25 (2001). https://doi.org:10.1016/s1534-5807(01)00022-3
48 Jamora, C. et al. Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell 98, 59-68 (1999). https://doi.org:10.1016/S0092-8674(00)80606-6
49 Jamora, C. 100 years of Golgi complexities. Trends Cell Biol 9, 37-38 (1999). https://doi.org:10.1016/s0962-8924(98)01419-6
50 Jamora, C. et al. Regulation of Golgi structure through heterotrimeric G proteins. Cell 91, 617-626 (1997).https://doi.org:10.1016/s0092-8674(00)80449-3
51 Jamora, C., Dennert, G. & Lee, A. S. Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci U S A 93, 7690-7694 (1996). https://doi.org:10.1073/pnas.93.15.7690
2 Hegde, A. et al. Extracellular Caspase-1 induces hair stem cell migration in wounded and inflamed skin conditions. J Cell Biol 223 (2024). https://doi.org:10.1083/jcb.202306028
3 Dutta, A., Saha, D. & Jamora, C. Approaches to Study Wound-Induced Hair Neogenesis (WIHN). Methods Mol Biol (2024). https://doi.org:10.1007/7651_2024_522
4 Asokan, M. S. et al. Immunogenicity of SARS-CoV-2 vaccines BBV152 (COVAXIN(R)) and ChAdOx1 nCoV-19 (COVISHIELD) in seronegative and seropositive individuals in India: a multicentre, nonrandomised observational study. Lancet Reg Health Southeast Asia 22, 100361 (2024). https://doi.org:10.1016/j.lansea.2024.100361
5 Rana, I. et al. Mindin (SPON2) Is Essential for Cutaneous Fibrogenesis in a Mouse Model of Systemic Sclerosis. J Invest Dermatol 143, 699-710 e610 (2023). https://doi.org:10.1016/j.jid.2022.10.011
6 Patlolla, N., Ponnachan, P., Jamora, C. & Abbey, D. Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor. Stem Cell Res 69, 103112 (2023). https://doi.org:10.1016/j.scr.2023.103112
7 Bhatt, T. et al. Niacinamide enhances cathelicidin mediated SARS-CoV-2 membrane disruption. Front Immunol14, 1255478 (2023). https://doi.org:10.3389/fimmu.2023.1255478
8 Zaarour, R. F. et al. The neuropeptide Substance P facilitates the transition from an inflammatory to proliferation phase-associated responses in dermal fibroblasts. Exp Dermatol 31, 1188-1201 (2022). https://doi.org:10.1111/exd.14573
9 Sobecki, M. et al. Vaccination-based immunotherapy to target profibrotic cells in liver and lung. Cell Stem Cell 29, 1459-1474 e1459 (2022). https://doi.org:10.1016/j.stem.2022.08.012
10 Hajam, E. Y. et al. The expanding impact of T-regs in the skin. Front Immunol 13, 983700 (2022). https://doi.org:10.3389/fimmu.2022.983700
11 Bhatt, T. et al. Initiation of wound healing is regulated by the convergence of mechanical and epigenetic cues. PLoS Biol 20, e3001777 (2022). https://doi.org:10.1371/journal.pbio.3001777
12 Badarinath, K. et al. Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin. Cell Rep 40, 111390 (2022). https://doi.org:10.1016/j.celrep.2022.111390
13 Zaarour, R. F. et al. Role of Hypoxia-Mediated Autophagy in Tumor Cell Death and Survival. Cancers (Basel) 13(2021). https://doi.org:10.3390/cancers13030533
14 Saha, D., Thannimangalath, S., Budamakuntla, L., Loganathan, E. & Jamora, C. Hair Follicle Grafting Therapy Promotes Re-Emergence of Critical Skin Components in Chronic Nonhealing Wounds. JID Innov 1, 100041 (2021). https://doi.org:10.1016/j.xjidi.2021.100041
15 Rana, I., Badarinath, K., Zirmire, R. K. & Jamora, C. Isolation and Quantification of Mouse gammadeltaT-cells in vitro and in vivo. Bio Protoc 11, e4148 (2021). https://doi.org:10.21769/BioProtoc.4148
16 Gund, R., Zirmire, R., J, H., Kansagara, G. & Jamora, C. Histological and Immunohistochemical Examination of Stem Cell Proliferation and Reepithelialization in the Wounded Skin. Bio Protoc 11, e3894 (2021). https://doi.org:10.21769/BioProtoc.3894
17 Biswas, R. et al. Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells. Dev Cell 56, 761-780 e767 (2021). https://doi.org:10.1016/j.devcel.2021.02.020
18 Bhatt, T. et al. Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8. Cell Rep 29, 2546-2555 e2544 (2019). https://doi.org:10.1016/j.celrep.2019.10.090
19 Badarinath, K. et al. Interactions Between Epidermal Keratinocytes, Dendritic Epidermal T-Cells, and Hair Follicle Stem Cells. Methods Mol Biol 1879, 285-297 (2019). https://doi.org:10.1007/7651_2018_155
20 Pincha, N., Saha, D., Bhatt, T., Zirmire, R. K. & Jamora, C. Activation of Fibroblast Contractility via Cell-Cell Interactions and Soluble Signals. Bio Protoc 8, e3021 (2018). https://doi.org:10.21769/BioProtoc.3021
21 Pincha, N. et al. PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest 128, 1807-1819 (2018). https://doi.org:10.1172/JCI99088
22 Lee, P. et al. Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of gammadeltaT-cells. Elife 6 (2017). https://doi.org:10.7554/eLife.28875
23 Nakasaki, M. et al. The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis.Nat Commun 6, 8574 (2015). https://doi.org:10.1038/ncomms9574
24 Lee, D. J. et al. Regulation and Function of the Caspase-1 in an Inflammatory Microenvironment. J Invest Dermatol 135, 2012-2020 (2015). https://doi.org:10.1038/jid.2015.119
25 Ando, T. et al. Mast Cells Are Required for Full Expression of Allergen/SEB-Induced Skin Inflammation. J Invest Dermatol 135, 925 (2015). https://doi.org:10.1038/jid.2014.359
26 Kim, J. et al. p53 Induces skin aging by depleting Blimp1+ sebaceous gland cells. Cell Death Dis 5, e1141 (2014). https://doi.org:10.1038/cddis.2014.87
27 Aung, A. et al. 3D traction stresses activate protease-dependent invasion of cancer cells. Biophys J 107, 2528-2537 (2014). https://doi.org:10.1016/j.bpj.2014.07.078
28 Ando, T. et al. Critical role for mast cell Stat5 activity in skin inflammation. Cell Rep 6, 366-376 (2014). https://doi.org:10.1016/j.celrep.2013.12.029
29 Cowburn, A. S. et al. HIF isoforms in the skin differentially regulate systemic arterial pressure. Proc Natl Acad Sci U S A 110, 17570-17575 (2013). https://doi.org:10.1073/pnas.1306942110
30 Bhatt, T., Rizvi, A., Batta, S. P., Kataria, S. & Jamora, C. Signaling and mechanical roles of E-cadherin. Cell Commun Adhes 20, 189-199 (2013). https://doi.org:10.3109/15419061.2013.854778
31 Ando, T. et al. Mast cells are required for full expression of allergen/SEB-induced skin inflammation. J Invest Dermatol 133, 2695-2705 (2013). https://doi.org:10.1038/jid.2013.250
32 Xu, J. et al. Fusarisetin A: Scalable Total Synthesis and Related Studies. Chem Sci 3, 3378-3386 (2012). https://doi.org:10.1039/C2SC21308G
33 Kanemaru, K. et al. Epidermal phospholipase Cdelta1 regulates granulocyte counts and systemic interleukin-17 levels in mice. Nat Commun 3, 963 (2012). https://doi.org:10.1038/ncomms1960
34 Swamy, M., Jamora, C., Havran, W. & Hayday, A. Epithelial decision makers: in search of the 'epimmunome'. Nat Immunol 11, 656-665 (2010). https://doi.org:10.1038/ni.1905
35 Li, C. et al. Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8. Proc Natl Acad Sci U S A 107, 22249-22254 (2010). https://doi.org:10.1073/pnas.1009751108
36 Du, F. et al. Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation. Cancer Res 70, 10080-10089 (2010). https://doi.org:10.1158/0008-5472.CAN-10-0324
37 Baldo, C., Jamora, C., Yamanouye, N., Zorn, T. M. & Moura-da-Silva, A. M. Mechanisms of vascular damage by hemorrhagic snake venom metalloproteinases: tissue distribution and in situ hydrolysis. PLoS Negl Trop Dis 4, e727 (2010). https://doi.org:10.1371/journal.pntd.0000727
38 Mielgo, A. et al. The death effector domains of caspase-8 induce terminal differentiation. PLoS One 4, e7879 (2009). https://doi.org:10.1371/journal.pone.0007879
39 Lee, P. et al. Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature 458, 519-523 (2009). https://doi.org:10.1038/nature07687
40 Boutin, A. T. et al. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell 133, 223-234 (2008). https://doi.org:10.1016/j.cell.2008.02.038
41 Jamora, C. et al. A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol 3, e11 (2005). https://doi.org:10.1371/journal.pbio.0030011
42 Perez-Moreno, M., Jamora, C. & Fuchs, E. Sticky business: orchestrating cellular signals at adherens junctions. Cell 112, 535-548 (2003). https://doi.org:10.1016/s0092-8674(03)00108-9
43 Jamora, C., DasGupta, R., Kocieniewski, P. & Fuchs, E. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 422, 317-322 (2003). https://doi.org:10.1038/nature01458
44 Hoffman, L. M. et al. Targeted disruption of the murine zyxin gene. Mol Cell Biol 23, 70-79 (2003). https://doi.org:10.1128/MCB.23.1.70-79.2003
45 Jamora, C. & Fuchs, E. Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol 4, E101-108 (2002). https://doi.org:10.1038/ncb0402-e101
46 Jamora, C., Theodoraki, M. A., Malhotra, V. & Theodorakis, E. A. Investigation of the biological mode of action of clerocidin using whole cell assays. Bioorg Med Chem 9, 1365-1370 (2001). https://doi.org:10.1016/s0968-0896(01)00051-7
47 Fuchs, E., Merrill, B. J., Jamora, C. & DasGupta, R. At the roots of a never-ending cycle. Dev Cell 1, 13-25 (2001). https://doi.org:10.1016/s1534-5807(01)00022-3
48 Jamora, C. et al. Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell 98, 59-68 (1999). https://doi.org:10.1016/S0092-8674(00)80606-6
49 Jamora, C. 100 years of Golgi complexities. Trends Cell Biol 9, 37-38 (1999). https://doi.org:10.1016/s0962-8924(98)01419-6
50 Jamora, C. et al. Regulation of Golgi structure through heterotrimeric G proteins. Cell 91, 617-626 (1997).https://doi.org:10.1016/s0092-8674(00)80449-3
51 Jamora, C., Dennert, G. & Lee, A. S. Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci U S A 93, 7690-7694 (1996). https://doi.org:10.1073/pnas.93.15.7690